Both coaches made multiple changes for the match in the oppressive heat of Miami, with a host of stars on the bench.
Arsenal midfielder Declan Rice put England ahead with a goal from distance in the third minute and Ezri Konsa headed home to make it 2-0.
The game threatened to become embarrassing for France when Saka made it 3-0 after a swift break and the Arsenal man scored again in first-half stoppage time.
Deschamps, taking charge of France for the final time, told French TV channel M6 that the first-half display had been “catastrophic”, urging his men to show pride.
He made multiple substitutions at the start of the second half, bringing on Ousmane Dembele and Bradley Barcola.
He was rewarded almost instantly when Mbappe scored his ninth goal of the tournament to move clear of Lionel Messi at the top of the Golden Boot standings.
The game had now totally changed complexion and Barcola pulled another goal back.
Mbappe then netted his second of the game to become the all-time leading World Cup goalscorer with 22 goals – slotting home from Olise’s pass.
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