At least three different variants of COVID have been reported in New York, according to scientists at U.S. universities and the Centers for Disease Control and Prevention (CDC).
These include the ‘U.K. variant’ that has spread quickly through Britain and onto 101 countries around the world, and the South Africa variant that has given rise to concerns about vaccine resistance.
In addition, a new variant of COVID may be spreading rapidly in New York, according to a preprint report that has not yet been peer-reviewed.
Here is what we know about the variants that have emerged in the state.
New York’s New Variant—B.1.526
Researchers from the California Institute of Technology (Caltech) have called the variant B.1.526. In the preprint report, they said the variant shares mutations with other variants that have already been reported.
The variant was first detected in New York in November 2020, and scientists said its mutations appeared in around a quarter of all the COVID genomes they sequenced from the state in February.
The Caltech scientists discovered the variant using a software tool they developed specifically for studying COVID spike mutations called Variant Database.
Dr. David Ho, director of the Aaron Diamond AIDS Research Center, told the New York Times cases had been detected in Westchester, the Bronx, Queens, Manhattan and Brooklyn.
Ho said: “So it seems to be widespread. It’s not a single outbreak.”
The Caltech researchers found that the variant contains spike mutations such as E484K, which has been associated with vaccine resistance, and S477N, which “has been implicated to increase viral infectivity,” the pre-print report stated.
In addition, the New York Times reported another team at Columbia University also detected a new form of COVID is spreading in New York, though their report is not yet public. Newsweek has contacted Columbia University for comment.
Researchers are running COVID mutation surveillance programs amid concern surrounding the potential for variants to resist vaccines and other therapies.
Meanwhile, the Centers for Disease Control and Prevention (CDC) is currently tracking three COVID variants in the U.S., two of which have been detected in New York.
These are variants B.1.1.7, the U.K. variant that was reported in the U.S. at the end of 2020, and B.1.351, the ‘South Africa variant’ that emerged independently of the U.K. variant and was reported in the U.S. at the end of January 2021.
Scientists have reported that the U.K. variant is able to spread faster than previous variants while the South African variant may pose some resistance to existing vaccines.
Johannes Eisele/AFP/Getty
The UK Variant—B.1.1.7
According to the CDC’s variant tracker, as of Tuesday February 23 the U.K. variant has spread most widely throughout the U.S. compared to the others and has so far been detected in 45 out of 50 states. It is also present in 101 countries worldwide, the World Health Organization said in its weekly epidemiological update on Tuesday.
There have been 1,881 reported cases in the U.S. so far, but it is predicted to become the dominant form of COVID in the U.S. in March based on modeling, the CDC said in mid-January. In New York, there are currently 136 cases.
In January, the U.K. government’s NERVTAG virus threat committee stated “several new analyses” suggested the variant was associated with “increased disease severity” and also said the variant appeared to spread substantially faster than other variants.
The South Africa Variant—B.1.351
Meanwhile the South Africa variant had been reported in 46 cases in 14 states at the time of writing, though just one case has been reported in New York.
According to the CDC there is evidence to suggest the variant poses resistance to COVID vaccines due to a mutation in the variant’s spike protein.
A laboratory study published last Wednesday found it was not clear whether the Pfizer vaccine is effective against the variant based on how an artificial version of the variant reacted to the jab.
In addition, a January study by Moderna suggested a reduction in how well its own vaccine worked against B.1.351, though the company claimed its two doses would still be enough.
On Thursday, Pfizer and BioNTech announced they had begun evaluating the effectiveness of a booster dose of their COVID vaccine against emerging variants, while Moderna on Wednesday said it had shipped a COVID variant booster dose of its own to the National Institute of Health for trials.
